靳帅

2012年9月——2016年6月，在山东农业大学农学院获得学士学位。

2016年9月——2021年6月，在中国科学院遗传与发育生物学研究所攻读博士学位，导师为高彩霞研究员。

Co-first author:

Jin, S.¹, Zong, Y.¹, Gao, Q.¹, Zhu, Z., Wang, Y., Qin, P., Liang, C., Wang, D., Qiu, J., Zhang, F., and Gao, C*. (2019). Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice. Science 364, 292–295.

Jin, S.¹, Fei, H.¹, Zhu, Z.¹, Luo, Y.¹, Liu, J., Gao, S., Zhang, F., Chen, Y.H., Wang, Y., and Gao, C*. (2020). Rationally designed APOBEC3B cytosine base editors with improved specificity. Mol. Cell 79, 728-740.

Jin, S., Gao, Q., and Gao, C*. (2021a). An unbiased method for evaluating the genome-wide specificity of base editors in rice. Nat. Protoc. 16, 431-457.

Jin, S.¹, Lin, Q.¹, Luo, Y.¹, Zhu, Z.¹, Liu, G., Li, Y., Chen, K., Qiu, J.*, and Gao, C.* (2021b). Genome-wide specificity of prime editors in plants, Nat. Biotechnol. 10.1038/s41587-021-00891-x.

Lin, Q.¹, Jin, S.¹, Zong, Y.¹, Yu, H.¹, Zhu, Z., Kou, L., Wang, Y., Qiu, J., Li, J., and Gao, C.* (2021). High-efficiency prime editing with optimized, paired pegRNAs in plants, Nat. Biotechnol. 10.1038/s41587-021-00868-w.

Co-author:

Lin, Q.¹, Zong, Y.¹, Xue, C.¹, Wang, S., Jin, S., Zhu, Z., Wang, Y., Anzalone, AV., Raguram, A., Doman, JL., Liu, DR., Gao, C*. (2020) Prime genome editing in rice and wheat. Nat. Biotechnol. 38, 582-585.

Li, C.¹, Zong, Y.¹, Jin, S., Zhu, H., Lin, D., Li, S., Qiu, J., Wang, Y.*, Gao, C.*(2020) SWISS: multiplexed orthogonal genome editing in plants with a Cas9 nickase and engineered CRISPR RNA scaffolds. Genome Biol. 21, 141.

Zong, Y.¹, Song, Q.¹, Li, C., Jin, S., Zhang, D., Wang, Y., Qiu, J-L., Gao, C.* (2018) Efficient C-to-T base editing in plants using a fusion of nCas9 and human APOBEC3A. Nat. Biotechnol. 36, 950-953.

Li, C.¹, Zong, Y.¹, Wang, Y.¹, Jin, S., Zhang, D., Song, Q., Zhang, R., Gao, C.*, (2018) Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion. Genome Biol. 19, 59.