个人简历:
分别于2009年和2012年获得中国农业大学学士和硕士学位,2015年获得日本冈山大学博士学位。2016至2017年在中国科学院遗传与发育生物学研究所高彩霞课题组从事博士后研究,2018年至2022年在高彩霞课题组担任助理研究员,2022年至今在高彩霞课题组担任副研究员。2022年入选中科院青年创新促进会会员。
研究方向与兴趣:
植物基因组编辑技术的开发及在农业育种中的应用
发表文章列表:
1共同第一作者,*通讯作者
张瑞,高彩霞* (2021) 基于双碱基编辑系统的植物基因靶向随机突变技术. 植物学报, 56 (1), 50-55.
Zhang R1, Chen S1, Meng X1, Chai Z, Wang D, Yuan Y, Chen K, Jiang L*, Li J*, Gao C* (2021) Generating broad-spectrum tolerance to ALS-inhibiting herbicides in rice by base editing. Science China Life Sciences, 64(10): 1624-1633.
Xu Y1, Lin Q1, Li X, Wang F, Chen Z, Wang J, Li W, Fan F, Tao Y, Jiang Y, Wei X, Zhang R, Zhu QH, Bu Q*, Yang J*, Gao C* (2021) Fine-tuning the amylose content of rice by precise base editing of the Wx Gene. Plant Biotechnology Journal, 19, 11-13.
Das S, Alam Md M, Zhang R, Hisano S, Suzuki N* (2021) Proof-of-concept for the yadokari nature: a capsidless replicase-encoding but replication-dependent (+)ssRNA virus hosted by an unrelated dsRNA virus. Journal of Virology, 95, e00467-21.
Li C1, Zhang R1, Meng X1, Chen S, Zong Y, Lu C, Qiu JL, Chen YH, Li J*, Gao C* (2020) Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors. Nature Biotechnology, 38(7):875-882. (Recommended in F1000Prime).
Xing S1, Chen K1, Zhu H, Zhang R, Zhang H, Li B, Gao C* (2020) Fine-tuning sugar content in strawberry. Genome Biology, 21, 230.
Zhang R1, Liu J1, Chai Z, Chen S, Bai Y, Zong Y, Chen K, Li J, Jiang L*, Gao C* (2019) Generation of herbicide tolerance traits and a new selectable marker in wheat using base editing. Nature Plants, 5, 480-485.
Chen K1, Wang Y1, Zhang R, Zhang H, Gao C* (2019) CRISPR/Cas Genome editing and precision plant breeding in agriculture. Annual Review of Plant Biology, 70, 667-697.
Li C1, Zong Y1, Wang Y1, Jin S, Zhang D, Song Q, Zhang R, Gao C* (2018) Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion. Genome Biology, 19, 59.
Hisano S, Zhang R, Faruk MI, Kondo H, Suzuki N* (2018) A neo-virus lifestyle exhibited by a (+)ssRNA virus hosted in an unrelated dsRNA virus. Virus Research, 244, 75-83.
Zong Y1, Wang Y1, Li C, Zhang R, Chen K, Ran Y, Qiu J, Wang D, Gao C* (2017) Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion, Nature Biotechnology, 35, 438-440. (Recommended in F1000Prime).
Zhang R1, Hisano S1, Tani A ,Kondo H, Kanematsu S, Suzuki N* (2016) A capsidless ssRNA virus hosted by an unrelated dsRNA virus. Nature Microbiology, 1(1):15001.
Zhang R1, Liu S1,Chiba S, Kondo H, Kanematsu S, Suzuki N* (2014) A novel single-stranded RNA virus isolated from a phytopathogenic filamentous fungus, Rosellinia necatrix, with similarity to hypo-like viruses. Frontiers in Microbiology, 5, Article 360 pp1-12.