Curriculum vitae:
B.S., South China Normal University, 2010
M.D., South China Normal University, 2014
Ph.D., Institute of Genetics and Developmental Biology (IGDB, CAS), 2017.
Post-Doctoral Fellow, Institute of Genetics and Developmental Biology (IGDB, CAS), 2021
Research direction and interest:
List of published articles:
1. Huang, J.#, Lin, Q.#, Fei, H.#, He, Z.#, Xu, H., Li, Y., Qu, K., Han, P., Gao, Q., Li, B., Liu, G., Zhang, L., Hu, J., Zhang, R., Luo, Y., Ran, Y., Qiu, J.-L., Zhao, K. T.*, and Gao, C.* (2023). Discovery of deaminases functions by structure-based protein clustering. Cell 186, 3182-3195.e14.
2. Lin, Q.#, Zong, Y.#, Xue, C.#, Wang, S., Jin, S., Zhu, Z., Wang, Y., Anzalone, A.V., Raguram, A., Doman, J.L., Liu, D.R., and Gao, C.* (2020). Prime genome editing in rice and wheat. Nat. Biotechnol. 38, 582-585.
3. Lin, Q.#, Jin, S.#, Zong, Y.#, Yu, H.#, Zhu, Z., Liu, G., Kou, L., Wang, Y., Qiu, J.L., Li, J.*, and Gao, C.* (2021). High-efficiency prime editing with optimized, paired pegRNAs in plants. Nat. Biotechnol. 39, 923-927.
4. Jin, S.#, Lin, Q.#, Luo, Y.#, Zhu, Z.#, Liu, G., Li, Y., Chen, K., Qiu, J.L., and Gao, C.* (2021). Genome-wide specificity of prime editors in plants. Nat. Biotechnol. 39, 1292-1299.
5. Wang, S.#, Zong, Y.#, Lin, Q.#, Zhang, H.#, Chai, Z., Zhang, D., Chen, K., Qiu,J.L., and Gao, C.* (2020). Precise, predictable multi-nucleotide deletions in rice and wheat using APOBEC-Cas9. Nat. Biotechnol. 38, 1460-1465.
6. Jin, S.#, Lin, Q.#, and Gao, C.* (2023). Optimized prime editing in monocot plants using PlantPegDesigner and engineered plant prime editors (ePPEs). Nat. Protoc. 18, 831-853.
7. Liu, G.#, Lin, Q.#, Jin, S.#, and Gao, C.* (2022). The CRISPR-Cas toolbox and gene editing technologies. Mol. Cell 82, 333-347.
8. Xu, Y.#, Lin, Q.#, Li, X., Wang, F., Chen, Z., Wang, J., Li, W., Fan, F., Tao, Y., Jiang, Y., Wei, X., Zhang, R., Zhu, Q.H., Bu, Q.*, Yang, J.*, and Gao, C.* (2021). Fine-tuning the amylose content of rice by precise base editing of the Wx Gene. Plant Biotechnol. J. 19, 11-13.
9. Lin, Q.#, Zhu, Z.#, Liu, G.#, Sun, C., Lin, D., Xue, C., Li, S., Zhang, D., Gao, C., Wang, Y.*, and Qiu, J.L.* (2021). Genome editing in plants with MAD7 nuclease. J. Genet. Genomics. 48, 444-451.
10. Lin, Q.#, Zhou, Z.#, Luo, W., Fang, M., Li, M.*, and Li, H.* (2017). Screening of proximal and interacting proteins in rice protoplasts by proximity-dependent biotinylation. Front. Plant Sci. 8, 749.
11. Xue, C.#, Zhang, H.#, Lin, Q., Fan, R., and Gao, C.* (2018). Manipulating mRNA splicing by base editing in plants. Sci. China Life Sci. 61, 1293-1300.
12. Jiang, Y.#, Chai, Y.#, Lu, M.#, Han, X., Lin, Q., Zhang, Y., Zhang, Q., Zhou, Y., Wang, X., Gao, C.*, and Chen, Q.J.* (2020). Prime editing efficiently generates W542L and S621I double mutations in two ALS genes in maize. Genome Biol. 21, 257.
13. Li, M.#, Li, X.#, Zhou, Z., Wu, P., Fang, M., Pan, X., Lin, Q., Luo, W., Wu, G.*, and Li, H.* (2016). Reassessment of the Four Yield-related Genes Gn1a, DEP1, GS3, and IPA1 in Rice Using a CRISPR/Cas9 System. Front. Plant Sci. 7, 377.
14. 罗婉冰, 林秋鹏, 李晓霞, 周泽娇, 阳辉勇, 杜荣裕, 李洪清.* (2017). 采用CELⅠ酶粗提物高效鉴定CRISPR/Cas9介导的基因突变. 生物工程学报 33, 775-784.
