GAO LAB
Plant Genome Editing
  • 2023 Annual Year-End Summary Meeting of the Gao Caixia Research Group
  • A Gao lab paper was selected for 'Best of Cell 2023'
  • Dr. Xue Chenxiao spoke at the 2023 Graduation Ceremony
  • Lab trips to Shidu in 2021
  • Congratulations to Shuai Jin on winning the 2021 Ray Wu Prise!

Representative Papers

Huang et al., Cell, 2023
Discovery of deaminase functions by structure-based protein clustering
Li et al., Nature, 2022
Genome-edited powdery mildew resistance in wheat without growth penalties
Zong et al., Nature Biotechnology, 2022
An engineered prime editor with enhanced editing efficiency in plants
Gao, Cell, 2021
Genome engineering for crop improvement and future agriculture
Jin et al., Nature Biotechnology, 2021
Genome-wide specificity of prime editors in plants
Lin et al., Nature Biotechnology, 2021
High-efficiency prime editing with optimized, paired pegRNAs in plants
JIn et al., Molecular Cell, 2020
Rationally Designed APOBEC3B Cytosine Base Editors with Improved Specificity
Li et al., Nature Biotechnology, 2020
Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors
Wang et al., Nature Biotechnology, 2020
Precise, predictable multi-nucleotide deletions in rice and wheat using APOBEC–Cas9
Lin et al., Nature Biotechnology, 2020
Prime genome editing in rice and wheat
Zhu et al., Nature Reviews Molecular Cell Biology, 2020
Applications of CRISPR–Cas in agriculture and plant biotechnology
Chen et al., Annual Review of Plant Biology, 2019
CRISPR/Cas Genome Editing and Precision Plant Breeding in Agriculture
Jin et al., Science, 2019
Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice
Zong et al., Nature Biotechnology, 2018
Efficient C-to-T base editing in plants using a fusion of nCas9 and human APOBEC3A
Li et al., Nature Biotechnology, 2018
Domestication of wild tomato is accelerated by genome editing
Zhang et al., Nature Biotechnology, 2018
Genome editing of upstream open reading frames enables translational control in plants
Zong et al., Nature Biotechnology, 2017
Precise base editing in rice, wheat and maize with a Cas9- cytidine deaminase fusion
Wang et al., Nature Biotechnology, 2014
Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew
Shan et al., Nature Biotechnology, 2013
Targeted genome modification of crop plants using a CRISPR-Cas system